An example of medication administration is:

Medication administration involves the actual process of delivering medication to a client. This includes not only the physical act of providing the medication but also ensuring that it is applied or consumed correctly according to prescribed guidelines. Rubbing a prescribed medicated cream onto the client's skin is a direct application of the medication, which constitutes administration because it involves delivering the therapeutic substance directly where it is needed.

The other options do not meet the criteria for medication administration. Handing an opened medication bottle to the client does not involve the act of giving the medication as per guidelines or assessing the client’s condition during the process. Simply informing the client that it is time to take their medication is related to communication but does not constitute administration. Discussing side effects is certainly an important aspect of medication management, but it pertains to patient education rather than the act of administering the medication itself.